A Hemorrhagic Diathesis Due to a Qualitative Platelet Defect

A hemorrhagic diathesis due to a qualitative platelet defect.

Severe thrombocytopenia and hemorrhagic diathesis due to brucellosis.

BACKGROUND We aimed to examine cases of brucellosis that presented with severe thrombocytopenia and hemorrhagic diathesis. METHODS A total of 10 brucellosis cases with severe thrombocytopenia were included in this case-series study. Patients' files were reviewed for their clinical and laboratory findings, as well as clinical outcomes and complications. Platelet counts of < 20,000/mm³ were dia...

Diathesis Associated with a Qualitative Platelet Factor V Deficiency

Studies were performed on a FrenchCanadian family afflicted with a bleeding disorder exhibiting an autosomal dominant inheritance pattern and a severe bleeding diathesis after trauma. Clinical laboratory coagulation tests were unimpressive; the only persistent abnormalities include mild thrombocytopenia and moderately reduced Factor V clotting activities. Some individuals had prolonged Stypven ...

Hemorrhagic diathesis due to a circulating anticoagulant. Report of case with laboratory observations.

OZNER, JOLLIFE AND TAYLOR’ first described, in 1940, a case of bleeding tendency resulting from the presence of an anticoagulant in the patient’s circulation. Since then the appearance of 1 1 additional case reports of this unusual hemorrhagic diathesis has given an opportunity to study previously unknown, abnormal mechanisms of blood coagulation.2’3 It has recently been pointed out’4 that thes...

Factor V (Quebec): a bleeding diathesis associated with a qualitative platelet Factor V deficiency.

Studies were performed on a French-Canadian family afflicted with a bleeding disorder exhibiting an autosomal dominant inheritance pattern and a severe bleeding diathesis after trauma. Clinical laboratory coagulation tests were unimpressive; the only persistent abnormalities include mild thrombocytopenia and moderately reduced Factor V clotting activities. Some individuals had prolonged Stypven...